Microfluidizer

Microfluidizer Lab Scale M-110P

Microfluidics

LAB SCALE M-110P?Plug and Play? Biopharma Lab Scale HomogenizerM-110P Microfluidizer for Continuous High Shear cGMP-Ready Fluid ProcessingThis new lab-scale model was developed to meet the needs for cGMP processing of small batch sizes. Utilizing Microfluidizer fixed-geometry interaction chamber technology and a ceramic plunger, the M-110P processes a wide variety of fluids, including oil-in-water emulsions, solids-in-liquid suspensions, and cell disruption of bacteria and the most difficult cells, like yeast ? in as few as one or two passes. What?s more, the process is repeatable and guaranteed to scale up to pilot and/or production volumes.HOW IT WORKSThe M-110P models contain an on-board 1.5 kW (2 HP) electric/hydraulic drive that powers a single-acting intensifier pump. By adjusting process pressures from 138 ? 2068 bar (2,000 ? 30,000 psi), the process can be optimized to achieve the desired results.The intensifier pump drives the product at constant pressure through the interaction chamber. The product stream accelerates to high velocities as it goes through the fixed-geometry microchannels, creating high shear and impact forces that produce the appropriate results.After leaving the interaction chamber, the product flows through the external cooling coil. Once the desired temperature is achieved, the product may be recirculated for further processing or advanced to the next step in the process.RECOMMENDED USESThe M-110P benchtop homogenizer model is recommended for: Stable NanodispersionsStable NanoemulsionsCell Rupture/ Cell Disruption (yeast, E. coli, etc.)Microencapsulation in Polymers, Liposomes and OilsDeagglomerationUNIQUE BENEFITSThe ?Plug and Play? M-110P laboratory Microfluidizer:Requires a minimum sample size of 36 mlAchieves processing pressures up to 2068 bar (30,000 psi)Produces product flow rate up to 120 ml/min (100 ml/min on 50 Hz model)Meets ASME-BPE compliance standardIs cGMP readyFeatures tube-in-tube pharma-grade heat exchangerContains inlet and outlet thermocouples with display on touch screenIncludes pressure transducer with display on touch screenProvides a 7" HMI color touch screen controlOffers the highest shear rateGuarantees scalabilityMeets CE marking requirementsOffers customizable options to suit every applicationSTANDARD FEATURES300 ml glass feed reservoirDiamond interaction chamberCeramic (Zirconia) plungerStainless steel enclosureElectric/hydraulic drive methodStandard one-year warrantyOPTIONAL FEATURES400 ml stainless steel open reservoir1 liter stainless steel open reservoir2 liter stainless steel open reservoir2 liter pressurized stainless steel reservoir7.6 liter pressurized stainless steel feed tankManual priming and purging cylinderSeal quench systemAdditional interaction chamberAdditional auxiliary processing module (ceramic)IQ/OQ on-site executionFAT, SAT, on-site startup and operator trainingPreventive maintenance serviceExtended warranty