NanoSpire, Inc. was founded in December, 2001 to commercialize a new generation of cavitation reentrant jet-based high shear nanotechnology tools and processes. NanoSpire provides the first nanotechnology tools capable of low nanometer, high-shear particle milling by harnessing and directing the energy of cavitation microjets. NanoSpire technology can be used for a wide range of nanofabrication applications.