RAM55 Pharma Production Mixer

By Resodyn Acoustic Mixers, Inc.

The Ultimate Scale for Pharmaceutical Production The RAM55 Pharma is the pinnacle of Resodyn's pharmaceutical production mixer lineup — delivering the full, transformative power of ResonantAcoustic® Mixing at a scale capable of supporting the largest commercial pharmaceutical manufacturing operations in the world. With a batch payload capacity of up to 924 lbs (420 kg), the RAM55 Pharma's digitally controlled, multiple processing capabilities multiply RAM's value through direct and easy scale-up from bench development to larger-scale batch production. The RAM55 Pharma enables the manufacture of a broad range of pharmaceutical products for less cost, more efficiently, more consistently, more uniformly, with less waste, and often with unprecedented results. Need a custom solution? All mixers can be customized for unique automations and applications. Enormous Mixing Capacity for Pharmaceutical Production The RAM55 does an enormous amount of work and produces results to match. RAM's bladeless system eliminates the extensive waste of material and time associated with traditional systems. Vessels are available in a variety of materials and up to 55 gallons (208 L) of capacity. It generally uses less power than other mixers of equivalent capacity. For large-scale pharmaceutical manufacturers — producing tablets, capsules, topical formulations, biologics, and other complex drug products — the RAM 55 Pharma eliminates the bottlenecks, quality variability, and compliance burdens that have long been associated with conventional impeller-based mixing at scale. Key Processing Capabilities - Processes up to 920 lb (417 kg) per batch - Handles solids, powders, liquids, gases, and viscous materials - Supports milling, grinding, sieving, and coating - Enables temperature control - Offers vacuum processing - Provides real-time monitoring and downloadable data for analysis - Stores up to 100 recipes for repeatable operations Key Advantages - 10–100x faster processing compared to traditional mixers - Highly repeatable results for consistent product quality - Direct scalability across the RAM product line - Exceptional ingredient distribution - Proven performance across global industries and applications Specifications General Model RAM55 Pharma Technology ResonantAcoustic® Mixing Intended Use Batch Mixing of Non-Hazardous Materials Unit Dimensions 10.5’ H x 15’ W x 10’ D (m: 3.2 x 4.57 x 3.05) Unit Weight Configuration-dependant Country of Origin USA Certifications Available CE, UL, CFR 21 Part 11 Operating Specifications Maximum Payload Capacity 920 lb (417 kg) Compatible Materials Solids, Liquids, Pastes, High Viscosity Max Vessel Acceleration 100g at approximately 60 Hz Temperature Control 200°F (93.3°C) to 23°F (-5°C) Vacuum Control 10 Torr Max Operating db > 80 db at 3’ Included Vessel Holder Assembly Application Specific Included Vessels Application Specific Control Specifications Human Machine Interface Full Color Touch Screen Operating System RAMWare™ Programable Mix Recipe Storage Yes Data Logging Yes Remote Operation Optional Control Features Up to 100 stored recipes, live monitoring, acceleration control Power Specifications Required Voltage 480 / VAC 60 Hz/3 Phase Documents - RAM55 product data sheet - McAlester Army Ammunition Plant's New Facility Accessories The RAM55 Pharma Production Mixer can be configured exactly how you need it. The Largest, Most Powerful Acoustic Mixer for Pharmaceutical Processing in the World Seamless Scale-Up from Bench to Batch One of the most significant advantages of the RAM 55 Pharma is how faithfully it preserves the formulation quality and process parameters established during early-stage R&D. RAM technology scales easily without additional testing from development to pilot to production scales — meaning the content uniformity, API distribution, and mixing profiles achieved on a PharmaRAM II or OmniRAM Pharma translate directly to the RAM 55 Pharma without costly revalidation or reformulation. This dramatically compresses the time between drug development and commercial launch. Contamination-Free, Sealed-Vessel Production The RAM 55 Pharma's bladeless, non-contact mixing architecture is particularly valuable at commercial production scale. Because mixing occurs in sealed containers using vibrational energy rather than impellers or blades, cross-contamination, operator exposure risks, and cleaning validation burdens are all minimized — all crucial for GMP compliance. For manufacturers producing multiple drug products on the same equipment, or working with highly potent APIs (HPAPIs), this is a decisive safety and regulatory advantage. Continuous Acoustic Mixing for Maximum Throughput Continuous Acoustic Mixing (CAM) systems are configurable for the RAM 55 Pharma and are custom built for the application, enabling high-throughput acoustic mixing of powders, pastes, and liquids without interruption. Resodyn's Continuous Acoustic Mixer creates ongoing production capacity of up to thousands of kilograms per hour — giving pharmaceutical manufacturers the throughput to meet global demand while maintaining the exacting uniformity and quality standards that patient safety requires. Trusted by the World's Leading Pharmaceutical Companies Resodyn Acoustic Mixers is the only company in the world to offer RAM technology, and provides pharmaceutical mixers geared toward the specific needs of pharmaceutical and medical industries. Resodyn has worked with demanding customers including well-known pharmaceutical manufacturers and top research institutions, all of whom rely on RAM's unique combination of speed, quality, and scalability to bring better medicines to market faster. The RAM 55 Pharma is not simply the largest pharmaceutical mixer Resodyn makes — it is the culmination of decades of acoustic mixing science, pharmaceutical industry expertise, and engineering excellence, all produced in Butte, Montana by one of the most innovative manufacturing companies in the American West. What is the RAM55 Pharma used for? The RAM 55 Pharma is a large-scale pharmaceutical acoustic mixing system designed for commercial production, pilot manufacturing, and advanced formulation processing in regulated pharmaceutical environments. What types of materials can the RAM55 Pharma process? The RAM 55 Pharma is designed to process a wide range of pharmaceutical materials, including powders, granules, slurries, suspensions, gels, creams, and high-viscosity pastes. What is the maximum batch capacity of the RAM55 Pharma? The standard capacity is rated at 920 lb (417 kg). But this is not the whole story. Capacity is affected by the material itself and its rheological properties, by the acceleration at which you are processing, and even the weight of your container. Your capacity could be significantly higher or lower than 920 lb (417 kg). Speak to your sales representative about your material and schedule a mix test for an accurate capacity based on your application details. How does acoustic mixing differ from traditional mixing methods? Acoustic mixing is the proven method of superior mixing and processing. It is bladeless, and is driven by vertical oscillation of the mix vessel at ~60 Hz and acceleration up to 100 g. Because the machine operates at resonance, it is energy efficient. The high energy motion drives mixing energy throughout the mix vessel for rapid and homogenous results beyond what conventional mixing can achieve. Traditional mixing methods vary, but generally rely on spinning paddles, tumbling vessels, or kneading action. Each method has significant limitations due to uneven energy distribution, excessive heat generation, slow processing, and material segregation. Simple mixing applications may achieve a suitable result, but the advanced processing needs commonly found in energetics, pharmaceuticals, advanced materials, batteries, additive manufacturing, and complex chemistries are often underserved by traditional mixing and processing methods. RAM is the processing technology that repeatedly solves the most difficult mixing, milling, coating, and chemical reaction challenges. What options are there for a RAM55 Pharma? The RAM 55 Pharma offers a variety of configurable options to support different pharmaceutical processing needs, including vacuum systems, jacketed vessels for temperature control, application-specific vessel designs, and automated process controls. Additional options include recipe storage, real-time process monitoring, data recording, material handling systems, and specialized vessel configurations for GMP and high-containment applications.