Plasma cleaning plays a critical role in advancing genomics research, particularly in next generation sequencing (NGS) and single cell sequencing applications. These cutting-edge genomic techniques demand a high level of cleanliness, and surface modification is often required for developing platforms. In both NGS and single-cell sequencing, plasma treatment is used to modify the surface chemistry of substrates to enhance the binding of biomolecules. This is particularly important when preparing sequencing surfaces to capture nucleic acids or other target molecules effectively. The modification can also improve the immobilization of probes and primers, which are essential for accurate sequencing.