Plasma treatment offers an efficient, chemical-free solution for cleaning glass surfaces, removing organic residues and improving optical performance. Beyond cleaning, plasma treatment also activates the glass surface, rendering it highly hydrophilic with a near-zero water contact angle. This activation provides uniform deposition and adhesion of surface coatings. Coatings such as bovine serum albumin (BSA) or polyethylene glycol (PEG) are commonly applied after plasma treatment to tether individual molecules to the surface, enabling advanced single-molecule and fluorescence-based assays. Plasma-treated glass slides are ideal for a wide range of life science applications, including surface functionalization, biosensing, and cell imaging. However, to maintain optimal surface activation, plasma treatment should be performed immediately prior to downstream steps to minimize hydrophobic recovery.
