Swiftly extract substances from plants, mushrooms and microorganisms. Ensure reproducible high-quality results on any scale, from lab to industrial. Replace harsh solvents with milder, greener food-grade alternatives and still achieve superior results. Maintain precise temperature control, making it possible to extract heat-sensitive substances. Handle a wide range of volumes, from a few milliliters to many hundreds of liters of biomass/solvent slurry at a time. Specifically designed for the most challenging and highest value extraction projects, ISM equipment combines the ability to deliver high-intensity ultrasound with a directly scalable process flow, which is unique in the industry. High-intensity ultrasound enables efficient, high-yield extraction of alkaloids, cannabinoids, terpenes, polyphenols, recombinant proteins, and many other bioactives. In many cases, harsh organic solvents can also be replaced with green alternatives, such as ethanol or water, while still providing superior results.