By Collaborative Drug Discovery - CDD Vault
Deliver higher-quality research with an electronic lab notebook (ELN) to organize, search, and share data in CDD Vault. Enable real-time collaboration, version control, and regulatory compliance. Capture, organize, and track every stage of your scientific workflow with a seamlessly integrated Electronic Lab Notebook (ELN) that connects your experiment data, inventory, and research assets in one secure platform. Whether you're managing complex biological assays or chemistry workflows, the ELN software from CDD improves collaboration, accelerates R&D productivity, and centralizes all your experimental data for long-term reliability. Record Experiments: Comprehensively document your research using text, tables, and files for product synthesis and assay development. Annotate images directly within your experimental write-ups. Standardize data capture across your organization with custom templates and versioning. Rapid Data Retrieval: Leverage the power of the electronic lab notebook to search and filter through your entries quickly. Our electronic lab notebook software makes finding the information you need easy and provides print-friendly options when a physical copy is necessary in the laboratory. Real-time Collaboration with Electronic Lab Notebook: Use your business rules, tasks, and alerts for real-time team coordination. Intellectual Property Protection: Secure your valuable research with our electronic lab notebook's legal compliance and audit tracking features. Witnessing and audit trails within the ELN are designed to safeguard all necessary information, protecting your intellectual property. Integration with Microsoft Office: Access and edit Microsoft Word, Excel and PowerPoint files online within the ELN software, enhancing documentation efficiency. Key Capabilities: Experiment Design & Laboratory Operations - Parallel Synthesis: Insert a reaction using R groups to depict variable sites on reagents and products. - Standardize Workflows with Templates: Capture necessary details without overwhelming users with extraneous content. - Streamlined Research Data Management: Document experiments with versatile content types, from text and tables to images and files. - Optimized Resource Management: Improve allocation and utilization of materials and equipment, reducing waste and costs. Data Access & Collaboration - Rapid Information Retrieval: Our electronic entries are easily searchable, filterable and printable, offering fast access to crucial data when needed. - Enhanced Collaboration: Share, annotate, and mentor in real-time across your team with customizable ELN forms to streamline your research processes. - Organizational Efficiency: Reduce time spent on manual record-keeping by linking directly to relevant entities. Integrity, Compliance & Safety - Increased Data Integrity: Ensure accurate, tamper-proof records for validation and peer review. - Regulatory Compliance and Safety: Adhere to industry standards and legal requirements (21 CFR Part 11), crucial for audits and IP protection. Easily view hazard and precautionary statements from PubChem's Laboratory Chemical Safety Summary (LCSS) page. For Biologists: Biologists work with a wide range of biological entities that can be challenging to keep track of. Our ELN software is designed to support the diverse nature of biological research, offering: - Complex Data Documentation: Easily capture detailed observational data, complex assay results and high-dimensional data. Our ELN systems support various data types, including sequences, genomics data, and microscopy images, facilitating comprehensive experiment documentation. - Collaborative Experimentation: Share findings, collaborate on data analysis and co-author documentation with colleagues around the globe. Real-time updates and annotations enable a dynamic research environment. - Regulatory Compliance and Data Integrity: Maintain compliance with regulatory standards like GLP and FDA guidelines. Our audit trails and electronic signatures ensure that your data meets all legal requirements for publication and patent applications. For a CRISPR gene editing workflow, an ELN can track guide RNA designs, experimental protocols, samples, editing results, and follow-up analyses in one connected record. This makes it easier to trace results back to the specific experimental conditions that produced them. For Chemists: Chemistry research, from medicinal chemistry to materials science, depends on accurate experimental records and well-structured data. An ELN designed for chemists can support workflows including: - Structured Experiment Templates: Standardize synthesis experiments, reaction conditions, and compound registration with customizable templates that improve consistency and reproducibility. - Chemical Data Management: Capture chemical structures, reactions, properties, and associated experimental data in one system, with integrated tools for structure drawing and calculations. For a synthesis workflow, an ELN can track each step from reaction setup through purification and final characterization, capturing reactant quantities, reaction conditions, procedures, and product yields along the way. Built-in calculations can automatically determine values such as molarities and masses, keeping the experimental record and associated chemical data connected in one place. Electronic lab notebook software employs advanced security measures, including encryption and access controls, to protect sensitive research data and intellectual property. While electronic lab notebook software is designed to be user-friendly, initial training is recommended to maximize efficiency and ensure users are familiar with all available features. For CDD Vault, our friendly support team provides expert training to new users at no additional cost. Electronic lab notebook software facilitates compliance with regulatory standards by providing audit trails, electronic signatures, and time-stamped records, which are essential for meeting the requirements of regulatory bodies. Embrace the future of scientific documentation and collaboration today with online electronic lab notebook software. Unlock unparalleled efficiency, security and real-time solutions tailored to your unique needs.

Visualization Transform complex data into clear, actionable insights with CDD Vault. Simplify interpretation, enhance collaboration, and accelerate discovery. Visualize your Science Data analysis and visualization doesn't have to be complicated. Enjoy the convenience of CDD Vault's built-in, easy-to-use suite of analytical tools. - Glean Insights from Data: Get more out of your data by graphing, filtering, and adding calculations on the fly to optimize lead identification. - Simplify Data Analysis: You can access key data analysis functionalities that you need most often right here in the CDD Vault, where your data lives. - Generate High Quality Graphs: Export visually appealing, high-resolution graphs in various formats for publication or presentation. - Share Your Insights: Once you identify an interesting pattern or lead, the Data Visualization session can be saved and shared with colleagues. Key Capabilities - Interactive graphing: Mine your data for hits, outliers and interesting relationships with interactive, dynamic histograms, scatterplots and radar plots complete with color coding and statistics. - Filtering and sorting: Large data sets can be filtered, sorted, and clustered by properties and experimental results, helping you identify what you are looking for. - Property calculations: Set up equations to automatically calculate derived results. Easily and routinely generate summary information, normalized activity, and compound selectivity. - Molecule optimization score: Score your molecules for lead optimization based upon the combination of important physiochemical properties. - Visual comparison: Compare up to four visualizations side-by-side. Look at the same data from different perspectives. Dynamically vary X/Y plotting, color and size mappings. - Customizable dashboards: Tailor how research data is displayed and analyzed to suit specific projects and workflows. How Does CDD Vault Facilitate Data Visualization in Research? CDD Vault offers a range of scientific data visualization tools that enable users to easily analyze and interpret their data, fostering better collaboration and more insightful discoveries.
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The CDD Vault Curves module is designed to help you efficiently analyze and visualize complex data. Curves streamlines your data processing and expresses complex trends concisely and visually. Whether you're a biologist or a chemist, this tool will make your research more impactful. Curves helps speed drug discovery in a number of ways, including: - Integration. Curves creates an automated workflow from raw inputs to plots, saving time and reducing errors. You can even import unprocessed data straight from your plate reader. - Presentation. Curves gives you full control over display options, including our color-coding feature that enhances visual clarity, enabling you to easily share, explore and export visualizations. - Comparison. Curves makes it easy to search across assays to evaluate trends and overlay topics crucial for identifying promising compounds. With the click of a button you can add multiple molecules or protocols to a single plot. - Collaboration. Curves enables you to securely share visualizations in a project-based environment. Our Plot Comments feature allows direct communication about specific data points. Color coordination for each curve makes it easy to visualize differences. - Curves Overlay. Our Curves Overlay feature gives you the ability to compare multiple results in one plot, with enhanced color coding. - Summary Curves. Our Summary Curves feature lets you convey results over time with a single toggle for quick decision making. - Curve Fits. Using our Curve Fits feature, you can analyze, selecting from a number of curve fit algorithms, including including our newly optimized bell-shaped fits for complex biological responses. - Calculations. You can use Curves to generate plots using raw, normalized and calculated values. Whether you're applying potency, selectivity, ADME, toxicity, PK or PD data, Curves will help you develop a clear, compelling, visual data story.
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Blueprints for sequences, structures, post translational modifications and function Go Beyond the Central Dogma CDD precisely represents post translational modifications like phosphorylation, glycosylation, methylation and acetylation. Chemically-aware biologics encodes modified oligonucleotides and amino acids. Self-Contained Sequence Representation (SCSR) using a V3000 mol file format provides several advantages, combining traditional sequence-based views with more detailed structural information. Examples Antibodies Register and annotate antibodies with their complete chemical structure, creating an exact record of the molecule, as well as a visual representation of its region and disulfide bridges. Oligonucleotides Register, annotate, and generate oligonucleotides, including support for duplexes, hairpins, strand breaks, and complex conjugates. Precisely visualize oligonucleotide modifications without footnotes. Proteins and Peptides Register proteins and peptides as fully defined chemical entities, preserving both their structural integrity and chemical properties. Conjugates Don't be limited to natural amino acids. Precisely represent ADCs, AOCs, APCs, and chimeras. Register conjugates with defined and variable attachment points.
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Manifold is the flagship product from PostEra, offering synthesis and search across every available molecule. Find retrosynthetic routes and conduct large-scale exact, similarity and substructure searches across the world's largest chemical spaces. Two ways to integrate CDD Vault with Manifold
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