By Institute for Advanced Chemistry of Catalonia (IQAC-CSIC)
Treat Strategies for therapy We develop innovative therapeutic strategies from the molecular to the preclinical level. Our research encompasses drug discovery, design of bioactive molecules, nanomedicine, and advanced delivery platforms, supported by AI-driven optimization and a wide range of biochemical, cellular, and animal studies. Key topics include - Computer-assisted synthesis and design of small molecules, peptides, and oligonucleotides - Advanced therapeutic approaches: - Photopharmacological, photothermal, and photomechanical tools - Supramolecular and multivalent agents - Protein degradation - Cellular immunotherapies and vaccines - Nanocarriers for targeted drug delivery: - Cell-derived nanostructures - Polymeric nanoparticles, peptides, lipid nanostructures, DNA nanostructures - Self-propelled nanosystems - AI/ML-enhanced nanosystem design, synthesis, and evaluation - Translational and preclinical models
