Manufacture uniform nanocrystals, nanoemulsions, and liposomes on laboratory, bench and industrial scales. Greatly increase the bioavailability and accelerate the onset of action of hydrophobic bioactive compounds. Extract active pharmaceutical ingredients from biomass by efficient cell disruption (lysis). Up to 40% of currently available bioactive substances and up to 70% of those under investigation by the pharmaceutical industry exhibit poor water solubility, resulting in low bioavailability and a delayed onset of action. Drug delivery platforms based on nanocarriers, such as nanocrystals, nanoemulsions, and liposomes, are very effective at overcoming these limitations. Industrial Sonomechanics® laboratory, bench, and industrial ultrasonic liquid processors provide a simple and effective means of producing uniform nanoparticles by exposing materials to high-intensity ultrasonic cavitation and the extremely strong shear forces it generates. These forces are also essential to the process of cell disruption (lysis), which is an important step in the extraction of pharmaceutical agents (e.g., recombinant proteins, medicinal oils, other bioactive substances) from yeast, bacterial and plant cells. With Industrial Sonomechanics® patented Barbell Horn® Ultrasonic Technology (BHUT), these processes can be easily implemented at any scale of operation, guaranteeing reproducible and predictable high-quality results.
