By Melbourne Centre for Nanofabrication
MALDI enables the ionization of molecules directly from samples on a target plate using a laser, making it suitable for analyzing a wide range of biomolecules such as proteins, peptides, lipids, and metabolites with high sensitivity and specificity. TIMS enhances the separation and characterization of ions based on their mobility in a buffer gas, allowing for improved resolution and more accurate identification of complex mixtures. The integration of these technologies in the timsTOF-fleX MALDI2 system offers researchers unparalleled capabilities for comprehensive analysis of biological samples, biomolecular imaging, and biomarker discovery in fields such as proteomics, metabolomics, and lipidomics. The Bruker timsTOF-fleX MALDI2 is a cutting-edge mass spectrometry system that combines two powerful technologies: MALDI (Matrix-Assisted Laser Desorption/Ionization) and TIMS (Trapped Ion Mobility Spectrometry).
