* PROTACs & Molecular Glues: Permeability, efflux profiling, ternary complex studies, linker stability, LC PRM MS characterization * Oligonucleotides: UV260/LC MS quantitation, n 1/n x metabolite mapping, biodistribution, Endosomal escape studies * ADCs: total antibody and free payload PK (HRMS/ELISA), conjugate ELISA quantification, linker stability, and catabolite mapping. * Peptides & Macrocycles: protease susceptibility, PAMPA peptide, HRMS confirmation * mRNA/LNP: particle size, lipid excipient profiling, biodistribution
Compiled from https://www.jubilantbiosys.com
