By Nanoscribe
Benefit from the design freedom, precision and printing power needed to produce precisely shaped microneedles and microneedle arrays with even sophisticated designs and custom materials. Nanoscribe's 3D microfabrication technology is ideally suited for rapid prototyping, aligned printing, mastering and small batch production. Microneedles are minimally invasive devices that are suitable for various use scenarios in medicine such as drug delivery, disease diagnosis and monitoring, and cosmetic applications. Microneedle geometry and shape have crucial influence in the microneedle performance and efficacy and their effective implementation into clinical trials. Novel and challenging designs require advanced and versatile microfabrication capabilities, in particular suitable materials, resolution, shape fidelity and printing speed. Two-Photon Polymerization is an established technology for 3D printing on the microscale and offers the design freedom in 3D needed to microfabricate shape-accurate single microneedle and microneedle arrays. The versatility of this technology enables to create microneedles with a wide range of design features: - High-aspect ratio structures - Microneedle arrays with variable periodicity and spatial distribution - Solid and hollow needles with symmetric and freeform shapes - Sharp tips and smooth surfaces with nanometer precision - Made of polymers, including biocompatible and biodegradable photopolymers Our microfabrication technologies offer the capabilities needed to fabricate almost any microneedle design. Our printers are suitable for the fabrication of prototypes with rapid iteration cycles, enabling fast modification of the shapes during the development steps. Thus, height, tip radius, base diameter, needle geometry and thickness as well as needle density in an array can be tuned according to the needed application. Hollow or solid, symmetric or freeform, sharp or blunt tips, smooth or structured needle surfaces, small or really large arrays – materialize your design. Nanoscribe’s microfabrication technologies are useful for rapid prototyping, aligned printing, mastering and small series production. The nano-, micro- and mesoscale structures can be used directly or serve as polymer masters for replication processes in industrial settings.
