GVD responded to an SBIR to innovate a coating solution that is able to reduce the force required to move the rubber stopper through the syringe as well or better than silicone oil, without the risk of affecting the solution inside. The results showed that GVD's PTFE coating, which is chemically inert, was lubricious and provided adequate friction reduction for ideal operation of a single-use syringe. Unlike silicone oil, GVD's PTFE coating does not breakdown or cause denaturing of therapeutics within a syringe. Also, GVD's PTFE coating is conformal in 3D, which overcomes challenges of common liquid phase coating methods that lack conformality in three dimensions. Lastly, GVD's PTFE coating is a low temperature coating process that does not degrade the rubber stopper materials within a syringe.
