Nanoelectrospray ionization technology Dedicated to Science, Dedicated to You Nanoelectrospray ionization technology The TriVersa NanoMate® LESA® is the latest in chip-based electrospray ionization technology from Advion Interchim Scientific®. It combines the benefits of liquid chromatography, mass spectrometry, chip-based infusion, fraction collection, and direct surface analysis into one integrated ion source platform. Obtain more information from complex samples than LC/MS alone The TriVersa NanoMate® integrates with: - Advion Interchim Scientific® ESI Chip® - LC/MS with Fraction Collection for Re-Analysis by Infusion Chip-based Direct Infusion and LC/MS Fraction Collection with Re-analysis by Infusion The TriVersa NanoMate® is the only automated ion source platform that allows high throughput infusion experiments for small or large analytes in applications ranging from shotgun lipidomics and non-covalent interaction studies (NCI) to protein characterization. The TriVersa NanoMate® was developed to operate as a nano-ESI ion source for LC/MS applications. Excess LC eluate can be utilized for additional fraction collection to create physical storage of the LC/MS experiment and allows re-analysis of fractions of interest as identified by the online LC/MS run.
Never Run Out of Nitrogen Again Unleash the power of precision with the Advion Interchim Scientific N₂ Gas Generator, crafted exclusively for the Advion Interchim Scientific expression® Compact Mass Spectrometer (CMS). This innovative generator ensures ultra-high purity nitrogen up to 99.9%, supporting peak laboratory performance with minimal noise and energy consumption. Its compact build, paired with a robust energy-saving mode, makes it the ideal solution for labs where space, efficiency, and reliability are paramount. Traditional nitrogen cylinders present well-known operational challenges: incremental gas loss due to imperfect sealing, a recurring demand for cylinder exchange, and reliance on external supply chains that introduce scheduling constraints and potential workflow disruptions. A delayed resupply can compromise continuity of LC/MS operations at a critical moment. The N₂ Gas Generator addresses these vulnerabilities directly, providing a continuous, on-demand nitrogen supply generated on-site — removing external dependencies and ensuring uninterrupted analytical performance. Primarily designed to supply mass spectrometers and flash and prepLC purification systems, this generator is suitable for any application requiring nitrogen purity levels up to 99.9%, with a maximum output of 15 L/min and a maximum pressure of 110 psi. How It Works The N₂ Gas Generator is equipped with a built-in compressor, making it entirely self-contained, and requires only a power supply to operate. Nitrogen is produced using fiber membrane technology, which separates nitrogen from the other components of compressed air. No external compressor. No gas lines. Just plug in the unit and you’re ready to go. Key Features - Continuous nitrogen supply — Uninterrupted flow for LC/MS and evaporation applications - High purity output — Up to 99.9% nitrogen purity, adjustable to your application needs Benefits - Plug-and-play operation — Minimal setup, no compressed air source required - No gas cylinders — Remove hazardous high-pressure cylinders from your lab environment - Quiet operation — Operates at ≤52 dB, ensuring a peaceful lab environment. - Compact design— Space-efficient dimensions with optional caster mobility. - Energy efficiency — Low power consumption (0.7 kW) and energy-saving mode. - User-friendly control — 7-inch Smart Interface touchscreen Applications - LC/MS (liquid chromatography–mass spectrometry) nebulizer and curtain gas - Solvent evaporation and sample concentration systems - Any laboratory process requiring nitrogen purity of up to 99.9% Compatible Advion Interchim Systems The N₂ Gas Generator pairs seamlessly with these systems: - Up to two expression® CMS Compact Mass Spectrometers - puriFlash® flash and prepLC purification system with evaporative light scattering detector (ELSD) - AVANT™ (U)HPLC system Specifications - Purity: Up to 99.5% - Flow Rate: Up to 15 L/min - Delivery Pressure: 110 psi - Outlet Connection: 1/4″ - Ambient Temperature: 5–35°C - Electrical Requirements: 110 V / 60 Hz or 220V/50Hz - Power Consumption: 0.7 kW, <10A current - Noise Level: ≤ 52 dB - Dimensions (H × W × D): 440 × 440 × 638 mm (560 mm H with casters) - Shipping Weight: 50 kg
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Mass-Directed Purification Dedicated to Science, Dedicated to You Reduce your purification workload up to 50%with the specificity of mass detection, no more fraction guesswork Time is precious in the lab. With mass-directed purification, chemists get pure compounds faster and with fewer steps—saving hours each week.Advion Interchim Scientific®already offers the industry-leading PrepLC-MS integration, and now seamlessly integrates our Flash purification offerings as well. With the puriFlash® XS 530 coupled with the express ion ® Compact Mass Spectrometer (CMS) you can: - Mass spectrometry allows simultaneous purification and compound characterization with mass-directed fraction collection - Collect only your peaks of interest - Reduce or eliminate the need for fraction analysis with confidence, knowing you collected your peak of interest - Reduce the burden of drying down unnecessary fractions The puriFlash®-CMS offers the benefits of compact mass spectrometry (CMS) for in-line, mass-directed fraction collection, providing users a more sensitive and accurate measure of fractions in real-time and a reliable detection method even when the analyte lacks a chromophore. The technology unambiguously identifies residual starting materials, desired product ions, side reactants and impurities by their molecular weight even in the presence of co-eluting compounds and solvent peaks. Offering both APCI or ESI ionization with positive and negative polarity, the addition of a mass spectrometer should be something every chemist should consider for the ultimate purification solution. Mass directed fraction collection greatly speeds up the chemist’s workflow with confidence in the content and purity of the collected fractions by eliminating off-line TLCs, workup, and core lab LC/MS assays. - Unique MS-interface design with a dynamic split and dilution valve for high flow rates and all column sizes without generating backpressure - Integrated post-split dilution to adjust the concentrations used in the MS source (no concentration limit – no signal saturation) - Normal & Reverse Phase - Normalized Scale signals MS, UV, ELSD (6 acquisition signals) Specifications puriFlash® MS for small molecule, synthetic organic chemists. Upgraded specs for pos/neg switching, faster scanning, and higher flow rate puriFlash® MS-HMW for large molecules – peptide synthesis, polymer chemistry and natural products Sources: APCI – (ESI option) APCI or ESI Patented API: orthogonal ion sampling from heated capillary – allows for small single turbo pump. Positive/Negative Ionization: Simultaneous Analysis Flow rate range ESI: 10 µL/min – 1 mL/min Flow rate range APCI: 10 µL/min – 2 mL/min mass range (m/z): 10 to 1200 (puriFlash® MS) / 10 to 2000 (puriFlash® MS-HMW) Scan rate (m/z-units per second): 10000 Resolution (m/z-units FWHM): 0.5 – 0.7 Sensitivity (SIM – S/N de 10 pg Reserpine, FIA 5 µl injection to 100 µl/min): 100:1 Accuracy (m/z): 0.1 Stability (m/z-units per 24 hour period: 18 – 24 °C): 0.1
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High performance compact mass spectrometer The family of expression® compact mass spectrometers (CMS) provides essential information quickly and improves the chemist's workflow. Modern organic labs have become automated, faster and more critical reactions require co-located versatile analytics — the expression® CMS solves this at an affordable price. Unrivaled utility and flexibility Most laboratories require the ability to analyze a range of samples using more than one technique for more complete identification and characterization of samples. The expression® CMS integrates with nearly every chemistry technique from the simplest, fastest direct probe analysis requiring no sample preparation to ultra-high performance compound separation with LC integration. The expression® CMS offers the most versatile sample techniques on the market, including: - Plate Express™ TLC Plate Reader - Atmospheric Solids Analysis Probe (ASAP®) - inert Atmospheric Solids Analysis Probe (iASAP) - Touch Express™ Open Port Sampling Interface (OPSI) - Volatile APCI (vAPCI) - AVANT™ Modular (U)HPLC - Direct Injection/Flow Injection Analysis (FIA) - Flow Chemistry - Flash Chromatography - Preparative Liquid Chromatography (Prep-LC) - Supercritical Fluids Chromatography (SFC) The family of expression® CMS was developed with maximum versatility in mind allowing users to switch rapidly between various sample introduction techniques with little sample preparation. The affordability, small size, and ease of use make them ideal for a variety of applications. - Reaction Monitoring - Teaching Chemistry - Food Safety and Ingredients Analysis - Cannabis & Hemp - Environmental Analysis - Clinical Diagnostics - Proteins and Peptides Synthesis - Forensics - And more Advion Interchim Scientific® offers solutions to fit your individual lab needs, including systems that support both m/z 10 – 1,200 units and m/z 10 – 2,000 units.
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The expression® Compact Mass Spectrometer (CMS), the standard for mass analysis in chemistry labs worldwide, is available with a teaching package offering professors the ability to provide students with industry-related knowledge and experience in mass spectrometry. The expression® CMS is ideal for students because of its small size, ease of use, and one-click software. When class is not in session, the system is ideal for use for research projects, making this a versatile choice for university labs seeking state of the art equipment paired with streamlined teaching modules. To bring mass spectrometry into the classroom, Advion Interchim Scientific® offers: - A compact, easy to use benchtop mass spectrometer for both students and researchers - Five hours of recorded lectures that go beyond the fundamentals of mass spectrometry to include various sample techniques, showing students real-world examples used in the chemistry workplace - Lecture slides to share or adapt to your own teaching style This teaching package includes ready-to-teach curriculum, making it the ideal solution for undergraduate and teaching chemistry programs. Lectures include: - Introduction to Mass Spectrometry: A lecture course on mass spectrometer instrumentation, ion source, ion detection and generation/interpretation of mass spectra - Flow Injection Analysis: Direct injection, including sample concentrations and guidelines, ESI and APCI hints, solvent considerations and examples - Direct probe sample introduction: Explaining the Atmospheric Solids Analysis Probe (ASAP®) including workflow, positive and negative ion switching, the effects of temperature and gas flow and example applications - Plate Express® TLC plate reader: Introducing direct mass analysis of TLC plates including system operation, normal phase and reversed-phase TLC plates, solvents and buffers and application data - LC/MS techniques: An introduction to liquid chromatography, HPLC system components and column choices, mobile phase flow rates and composition, LC/MS and solvent details - Other compact mass spec techniques: Flash, prep-liquid, SFC, flow and more
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