By Mecwins
Ultra-high sensitivity, several orders of magnitude better than conventional immunoassays — with remarkable throughput, multiplexing and a broad dynamic range. Optical reader & particle counter The plasmonic nanoparticles are optically detected by measuring the weak scattering signal with proprietary dark-field micro-spectrophotometry. Patents EP19382244, EP19382245 Count single molecules, one by one As each plasmonic nanoparticle binds specifically to a biomarker of interest, by classifying and counting the different nanoparticles it is possible to quantify the amount of each biomarker immobilized on the substrate. Pending EP19382245, EP19382244 Femtogram-range sensitivity High sensitivity in the femtogram range has been demonstrated for different biomarkers across therapeutic areas. - Oncology: PSA, biomarker for prostate cancer recurrence detection. - Cardiac diseases: Troponin I, biomarker of reference for Myocardial Infarction. - Infectious diseases: P24 biomarker for HIV detection. - Inflammation: Interleukin biomarkers (IL-10, IL-6, TNF-α). AVAC technical specifications - Spatial resolution: 0.7 µm (Diffraction-limited) - Reading / Analysis speed: Up to 20,000 images per hour - Throughput: 96 samples in less than 5 minutes - Multiplexing capability: Up to 5 biomarkers - User interface: Integrated 15” touch screen for all in- and outputs - Computer: Fully integrated high-performance computer - Weight: 95 Kg - Dimensions (H x D x W): 750 mm x 735 mm x 520 mm
