At Gillson Sciences, we offer multiple particle sizing techniques to meet the diverse needs of our clients. Whether working with nanoparticles or larger particulates, our methods deliver accurate, reproducible measurements for research, quality control, and regulatory compliance. Nano Tracking Analysis (NTA) Nano Tracking Analysis is used to visualize and measure nanoparticles in liquid suspensions. A laser illuminates the particles, and the scattered light is captured by a microscope and recorded in real time. By tracking the Brownian motion of individual particles and applying the Stokes-Einstein equation, NTA calculates sizes from 50 nm to 2 μm. This method is ideal for high-resolution visualization of particle populations in biologics, pharmaceuticals, and nanomaterials. Laser Diffraction Spectroscopy Laser diffraction measures particle size distribution by passing a laser beam through a sample and analyzing how light scatters. Larger particles scatter light at small angles, while smaller particles scatter at wider angles. Using Mie theory, we can determine sizes ranging from 20 nm to 2 mm. This method is well-suited for powders, suspensions, and emulsions, offering fast, accurate results across a wide size range. Dynamic Light Scattering (DLS) Dynamic Light Scattering, also known as photon correlation spectroscopy (PCS) or quasi-elastic light scattering (QLS), measures the Brownian motion of particles in a liquid. Fluctuations in scattered light intensity are analyzed with the Stokes-Einstein equation to calculate particle sizes from 10 nm to 2 μm. DLS is highly effective for characterizing nanoparticles, proteins, and colloidal systems.
