Accelerate your oligonucleotide drug development with Jubilant Biosys, possessing specialized expertise in synthesizing oligonucleotides of varying lengths & incorporating a variety of linkers for bioconjugation to carbohydrates and antibodies. Jubilant Biosys offers advanced oligonucleotide synthesis services under stringent process controls. Backed by extensive technical expertise, we provide a wide range of chemistries and modifications customized to specific oligonucleotide sequences. Additionally, we deliver oligonucleotide conjugates for diverse applications and constructs. Our capabilities include: - Oligonucleotide synthesis using automated oligonucleotide synthesizer - Custom DNA and RNA oligonucleotides synthesis - For various techniques such as PCR, antisense, siRNA, aptamer and CRISPR - Standard chemical modifications such as PS, 2′OMe, 2′F, 2′OMOE, LNA - Fluorescent oligonucleotides - Oligonucleotide conjugates (Small molecule, Carbohydrate, Lipid, Peptide) - Purification of oligonucleotides using anion-exchange and reversed-phase HPLC - Analysis of oligonucleotides through LCMS and NMR Oligonucleotide Platform - Monomer/linker/conjugate synthesis - Oligonucleotide LIbrary - Oligonucleotide Optimization - In vitro and in vivo efficacy/early tox screening, off-target - ADME and in vivo PK - Toxicology Instrumentation Capabilities - Automated oligonucleotide synthesis capability (mg – gram scale) - 12 column synthesizer - Solid phase synthesis using phosphoramidite approach
Compiled from https://www.jubilantbiosys.com
