What is PAT? Plasmonic Amplification Technology™ (PAT™) is a “double amplification system” that leverages the inherent properties of nano-based plasmonics enabling quantitative limits of detection and quantitation far lower than those achievable with current lateral flow based systems. LamdaGen’s nano-structured thin-film sensors have a plasmonically active surface with an extremely short sensing range. When targets bind to the sensor surface, the surface changes color, greatly amplifying the signal. In an immunoassay, a proprietary moiety-conjugate interacts with the sensor surface creating a powerful SECOND amplification. This “double amplification” is called PAT – Plasmonic Amplification Technology. PAT enables high sensitivity detection and is applicable to sandwich, competitive and other assay configurations. In addition, the sensor’s short plasmonic sensing range eliminates the need for a wash step, greatly simplifying assay workflow.
LAuRA (LamdaGen Au (gold) Rapid Assay) offers a turnkey plasmonic biosensing solution, combining the speed and convenience of lateral flow assays with the high sensitivity and quantitation of ELISA tests. The LAuRA Rapid Test System delivers laboratory quality results equivalent to gold standard ELISA’s in minutes rather than hours. LAuRA’s test procedure is simple and easy to use. Disposable cartridges can be designed to run single or multi-target tests and deliver results 15 minutes or less. Leveraging the inherent properties of advanced nano-based plasmonics, the LAuRA immuno-based platform provides high sensitivity detection capabilities far exceeding those of existing rapid assays. The patented platform is flexible and scalable, enabling uniquely powerful detection systems ranging from small benchtops to handhelds to throughput. Innovative LAuRA systems are being developed for applications in Human Health, Food & Water Safety, Biothreat Detection, and Animal Health.
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Continuous metallic thin-film plasmonic sensors LamdaGen's patented nano-structured thin-film sensors are made using pure gold. The sensors are grown at the angstrom level allowing exquisite control over their architecture and reproducibility. This nano-process produces plasmonic sensors that are burgundy in color. The sensor acts as a smart signal transducer, possessing significant amplification properties.A robust surface color change occurs when a target biomolecule binds to the sensor surface. The sensor surface has an extremely short sensing range (~30nm) which makes it blind to molecules outside of the range. This remarkably short sensing range makes the system highly amenable to a variety of complex media including biological fluids. Easily manufactured and scalable Highly reproducible and stable Grown at ambient temperature Compatible with a wide range of surfaces Adaptable to many form factors Easily multiplexed for multiple targets Low cost
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