PAQXOS

By Sympatec GmbH

As a common control and evaluation platform for all Sympatec systems, PAQXOS combines our accumulated metrological expertise in a user-friendly application software. PAQXOS provides automatic settings for all measurement parameters of particle size analysis, optimally adjusts them, checks the measurability of the sample before and during the measurement and outputs the signal quality for orientation during and after the measurement. The laser intensity and the positioning of the cuvette are adjusted to the respective application under software control before each measurement. This makes complex measurements very easy for the user and NANOPHOX CS is a practical instrument for valid particle size and particle stability measurement. A step-by-step wizard with built-in expert knowledge also leads the inexperienced user to successful measurements. PAQXOS provides graphical presentations, tables and paper reports that can be chosen from a variety of predefined and fully customisable formats. The intuitive graphical user interface supports the execution of reliable, meaningful measurements. The cross-correlation function, representing reproducibility and stability, is used to calculate the particle size distribution. In addition to the classic 2nd Cumulant evaluation PAQXOS offers a distinctly more efficient Non-Negative Least Square (NNLS) algorithm. The NNLS evaluation mode reliably presents polydisperse or bimodal samples with up to 256 size classes directly as volume or intensity-based distribution. Characteristic values such as the arithmetic or harmonic mean values (x harm) of single modes are directly available. Our versatile PAQXOS software is ideally suited for demanding production and research applications. An integrated scripting environment allows for the programming of elaborate routines to design repeat measurements in an efficient and reproducible manner. Furthermore, predefined measurement parameter settings may be implemented as binding Standard Operating Procedures | SOPs. Our software also meets the requirements of FDA-regulated pharmaceutical industries and provides all safety functions, access controls and authentication methods stipulated in regulation 21 CFR Part 11 regarding electronic records and electronic signatures to ensure data integrity and prevent manipulation of records.