Lipid nanoparticles are widely used in mRNA therapeutics, gene delivery, and nanomedicine formulations. These systems often contain heterogeneous particle populations that are difficult to resolve using ensemble techniques. Our separation-based approach enables detailed size distribution analysis of LNP formulations and allows detection of larger aggregates or secondary particle populations. Typical analyses include: • LNP size distribution • Separation of heterogeneous particle populations • Fraction collection for downstream analysis
