By ATDBio
Scalable oligonucleotide synthesis from micromole to millimole scale - Extensive backbone, sugar and conjugate modification capabilities - Tailored purification and analytical support - UK-based, ISO 9001 certified laboratory - Endotoxin testing available Therapeutic oligonucleotide projects often require advanced modifications, demanding purity specifications and tailored analytical methods. ATDBio combines scalable synthesis, tailored purification and analytical expertise to support even the most demanding projects. For more than 20 years, we have supplied oligonucleotides to pharmaceutical, biotechnology and research organisations worldwide. Supporting a range of therapeutic oligo modalities and delivery strategies: ASOs, siRNA, Aptamers, GalNAc Conjugates, Custom Therapeutic Oligos Development Stages Discovery: Synthesis scale 0.2 – 1 µmol; Mass delivered 0.1 – 2 mg; Lead time (estimate) 1 – 4 weeks Optimisation: Synthesis scale 10 – 50 µmol; Mass delivered 10 – 100 mg; Lead time (estimate) 2 – 6 weeks Preclinical: Synthesis scale 200 µmol – 1 mmol+; Mass delivered 200 mg – 2 g+; Lead time (estimate) 3 – 12 weeks
