By NanoBrand
Custom nanoparticle synthesis involves designing and producing gold or silver nanoparticles to meet the requirements of a specific application. Parameters such as particle size, shape, surface chemistry, concentration and optical properties are tailored for each project. NanoBrand’s scientific team supports development from initial feasibility studies through process optimization, scale-up and the delivery of application-ready material. All nanoparticles are manufactured in Canada and characterized lot by lot for properties such as size distribution, morphology, surface charge and optical response. NanoBrand’s scientific team designs and synthesizes gold and silver nanoparticles tailored to specific applications. Particle size, morphology, surface chemistry, concentration and plasmonic properties can be customized to meet defined performance requirements. Projects may range from early-stage feasibility studies and formulation development to application-ready materials for diagnostics, bioimaging and biosensing, as well as gold nanoparticles for drug delivery research. NanoBrand’s team includes experienced PhD scientists and chemists specializing in life-science nanotechnology and gold and silver nanoparticle development. What NanoBrand controls in Custom Synthesis Each parameter below can be specified for a project, based on capabilities NanoBrand already offers and verifies across its product catalogue. The table summarizes these capabilities; project-specific requirements are defined in collaboration with the client’s team. Parameter | What NanoBrand controls Material | Gold (AuNPs) and Silver (AgNPs) Particle Size | Catalogue gold spheres from 5 to 200 nm; custom sizes on request Size Distribution | Coefficient of variation (CoV) at or below 5 % and polydispersity index (PdI) at or below 0.1 on spherical gold of 10 nm and larger, as specified in the catalogue Shape | Spherical particles and branched gold nanostars Surface Chemistry | Citrate, PEG-carboxylate, PVP or chitosan on nanostars, stabilizer-free silver; custom surface chemistry available Optical Reponse | Set through size and shape Characterization Methods | TEM with EDS, DLS, Zeta potential, UV-vis and ICP-MS, through the characterization service Lot Data | Lot-specific characterization on every order; nanoparticles are characterized for core size, size distribution, hydrodinamic diameter, Zeta-potential and plasmon peak position Scale | Development quantities; bulk manufacturing under GMP guidelines once the specification is fixed Lead Time | 2 to 3 weeks on standard orders Manufactured in | Canada, at the NanoBrand facility Catalogue values reflect products NanoBrand currently offers. Custom projects are specified and evaluated using the same measurement criteria. What to provide, what you receive A custom synthesis project begins with your application requirements, not a catalogue part number. Depending on the agreed scope, NanoBrand delivers nanoparticles alone, a ready-to-test formulation, or nanoparticles accompanied by study data. What to provide | What you receive Intended application and performance targets | Proposed project specifications and quotation Buffer conditions and sample matrix | Gold or silver nanoparticles manufactured to the agreed specifications Target analyte or delivery route | Ready-to-test formulation, if formulation development is included Regulatory requirements for the final product | Lot-specific characterization data Existing formulation, if applicable | Antimicrobial, conjugation-efficiency, stability, or in vitro performance data, if testing is included
