Consists of optimizing the formulation for the indication of interest, for in vitro and/or in vivo assessment and validation, considering factors like identified biopharmaceutical problems, target dosage and route of administration. - Feasibility evaluation: Following the theoretical analysis, we delve into a feasibility study. Here, we validate the theoretical predictions under controlled conditions to ensure the compatibility of our drug delivery system with your molecule. This step is crucial in identifying the unique opportunities and possible challenges that may arise. This phase involves: - Physicochemical characterization: Mean size, PDI and Zeta Potential - Association efficiency - Stability during storage (at 4ºC for up to 48 hours and 37ªC for up to 4 hours) - Colloidal stability in a specific biological fluid - Evaluation point: The final say rests with you. After the feasibility study, you have the choice to proceed further based on the results. Should the results be promising, we would then proceed to the subsequent stages of development. However, if the results do not meet your expectations, you are free to opt out. This process allows us to place your molecule at the center of our efforts, providing a structured,to explore the potential benefits of our advanced drug delivery system. - Full product development
