NanoGetic SL provides a full range of services related ti customize nanoparticles (NPs).The company was founded to exploit the know-how of Founders in the flield of nanotechnology. The have developed a variety of protocols to prepare NPs based oncross-linked polystyrene including magnetic and fluorescently labeled products. These NPs by bio-orthogonal strategies following multi-step solid phase organic synthesis. – Preparation of multifuncionalized cross linked polystyrene NPs. – Mono-dispersed polymeric nanoparticles with selec: •Particle size (100nm-10 micrometers) • Size distribution • Surface modification • Capacidad de carga (high, medium or low) – Egineered nanoparticles (ENPs): • Our nanoparticles are designed to be flexible to be linked with different molecular tags. – Services of Scale Up Production of nanoparticles. NanoGetic expertise is focussed in scaling-up the production of nanoparticles. From small scale lab production to a reliable, safe and cost-effective standard protocol for big scale production following GMP. – Services of Quality Control of nanoparticles: – In Vitro Characterization: * Physico-chemical characterization: Size, Size distribution, Zeta Potential, pH of nanoparticle suspensions, Drug loading, Drug release in simple and complex media. * Stability in biological media * Microbial contamination * Endotoxin * Detection of Mycoplasma * Cytotoxicity * Immunotoxicity * Hemocompatibility – In Vivo Characterization: Toxicity and pharmacokinetic studies. In vivo imaging. Customized service. Design of a set of assays depending on the application of the nanomaterial. – Aplications: • Targeted drug delivery • Personalized medicine • Diagnostic • Basic research • Smart material
