Ultrastructural imaging capabilities offer significant potential for many translational studies This Magnify™ image was captured using a Nikon Eclipse Ti2 with a CSU-W1 spinning disk confocal module, Andor v.4.2 Zyla sCMOS camera, and a 40×/1.15 water immersion objective. The sample, a fully expanded human FFPE kidney tissue, was stained with DAPI (magenta), ACTN4 (orange), and WGA (blue), and rendered in 3D to showcase the detailed architecture of renal structures. Visualizing podocyte foot processes in 3D is crucial for understanding renal pathology and diagnosing kidney diseases. Magnify™ allows for high-resolution imaging of these delicate structures without the need for specialized microscopes, offering a powerful and accessible tool for renal pathology. By providing clear views of critical renal components like ACTN4 and WGA-labeled areas, Magnify™ enhances our ability to study kidney function and pathology, leading to better insights into disease mechanisms and potential treatments.
