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Image scanning microscopy based on multifocal metalens for sub-diffraction-limited imaging of brain organoids
In a new paper published in Light: Science & Applications, a research team led by Professor Inki Kim at the BioNanoPhotonics Laboratory in the Department of Biophysics, Institute of Quantum Biophysics, Sungkyunkwan University, developed a multifocal metalens based on a novel hybrid multiplexing approach to implement ISM and successfully captured super-resolution images of neuronal structures in brain organoids. The proposed hybrid multiplexing method combines two conventional


Nanoscale under gigapressure
Sometimes a change of perspective can make a world of difference. A team of scientists from PETRA III, Centre for X-ray and Nanoscience (CXNS) at DESY, and MAX IV has rearranged the method in which one can use an X-ray beam to image a sample without using high-quality lenses. The method, called ptychography, has been widely used at synchrotrons and free-electron lasers to analyse the inner workings of materials quickly enough while avoiding major damage to the sample by the X


New technique boosts electron microscope’s clarity
A team of researchers at the University of Victoria (UVic) have achieved a major breakthrough in electron microscopy that will allow scientists to visualize atomic-scale structures with unprecedented clarity using lower-cost and lower-energy microscopes than ever before. Led by Arthur Blackburn, co-director of UVic’s Advanced Microscopy Facility, the team developed a novel imaging technique that allowed them to achieve sub-Ångström resolution (less than one ten-billionth of a


New method instantly characterizes thousands of molecules
The new method, inspired by an imaging technique that has been around for 35 years, takes ultraprecise measurements of a molecule’s unique light-emission signature at the scale of a billionth of a second. It uses a single-photon avalanche diode (SPAD) camera made up of close to a million tiny sensors that can each detect aphoton. The data are analyzed to determine a molecule’s fluorescence lifetime – or the extremely short delay between an excitation laser pulse and the fluor


A new approach allows researchers to catch a photocatalyst in action
Now, writing in the journal Nature Communications, a team led by researchers at the Department of Energy’s SLAC National Accelerator Laboratory report how they used ultrafast X-rays from the Linac Coherent Light Source (LCLS), combined with recent theoretical advancements, to reveal those atomic motions on a timescale of femtoseconds, millionths of a billionth of a second. The technique could be used to observe speedy atomic motions in more complex catalysts.


A new age of electron microscopy: Magnifying possibilities with automation
“We now have a way for people to interact with a detector on one side and a supercomputer on the other side with a simple webpage called Distiller in the middle,” said Peter Ercius, interim facility director of the National Center for Electron Microscopy (NCEM) at Berkeley Lab’s Molecular Foundry. “We’re moving towards getting huge amounts of data processed in an automated way with minimal human intervention.”


Physicists capture elusive plasma instability in unprecedented detail
Plasma is a super-hot mixture of charged particles, such as ions and electrons, which can conduct electricity and are influenced by magne...


Prolonged super-microscopy: Nanographenes allow longer observation time
The 2014 Nobel Prize in Chemistry was awarded for the development of super-resolved fluorescence microscopy, including STED (Stimulated Emis


New method for improving nanoparticle size estimation
(a) Selected ground truth HAADF-STEM multislice image simulations. Scale bars are 1 nm. (b) Corresponding synthetic multislice images...


Molecular determinants of optical modulation in ssDNA-carbon nanotube biosensors
@ ACS Nano 2025, https://pubs.acs.org/doi/10.1021/acsnano.4c13814 Scrutinizing the underpinnings of optical modulation at the molecular...


Alternating triangular charge density wave domains observed within a layered superconducting compound
A research team consisting of NIMS and the Tokyo University of Science observed charge density waves (CDWs) within Niobium diselenide...


Attosecond core-level spectroscopy reveals real-time molecular dynamics
Chemical reactions are complex mechanisms. Many different dynamical processes are involved, affecting both the electrons and the nucleus...
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