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Image scanning microscopy based on multifocal metalens for sub-diffraction-limited imaging of brain organoids
In a new paper published in Light: Science & Applications, a research team led by Professor Inki Kim at the BioNanoPhotonics Laboratory in the Department of Biophysics, Institute of Quantum Biophysics, Sungkyunkwan University, developed a multifocal metalens based on a novel hybrid multiplexing approach to implement ISM and successfully captured super-resolution images of neuronal structures in brain organoids. The proposed hybrid multiplexing method combines two conventional
Nov 26, 20253 min read


Nanoscale under gigapressure
Sometimes a change of perspective can make a world of difference. A team of scientists from PETRA III, Centre for X-ray and Nanoscience (CXNS) at DESY, and MAX IV has rearranged the method in which one can use an X-ray beam to image a sample without using high-quality lenses. The method, called ptychography, has been widely used at synchrotrons and free-electron lasers to analyse the inner workings of materials quickly enough while avoiding major damage to the sample by the X
Nov 4, 20253 min read


New technique boosts electron microscope’s clarity
A team of researchers at the University of Victoria (UVic) have achieved a major breakthrough in electron microscopy that will allow scientists to visualize atomic-scale structures with unprecedented clarity using lower-cost and lower-energy microscopes than ever before. Led by Arthur Blackburn, co-director of UVic’s Advanced Microscopy Facility, the team developed a novel imaging technique that allowed them to achieve sub-Ångström resolution (less than one ten-billionth of a
Oct 17, 20252 min read


New method instantly characterizes thousands of molecules
The new method, inspired by an imaging technique that has been around for 35 years, takes ultraprecise measurements of a molecule’s unique light-emission signature at the scale of a billionth of a second. It uses a single-photon avalanche diode (SPAD) camera made up of close to a million tiny sensors that can each detect aphoton. The data are analyzed to determine a molecule’s fluorescence lifetime – or the extremely short delay between an excitation laser pulse and the fluor
Aug 6, 20253 min read


A new approach allows researchers to catch a photocatalyst in action
Now, writing in the journal Nature Communications, a team led by researchers at the Department of Energy’s SLAC National Accelerator Laboratory report how they used ultrafast X-rays from the Linac Coherent Light Source (LCLS), combined with recent theoretical advancements, to reveal those atomic motions on a timescale of femtoseconds, millionths of a billionth of a second. The technique could be used to observe speedy atomic motions in more complex catalysts.
May 23, 20254 min read


A new age of electron microscopy: Magnifying possibilities with automation
“We now have a way for people to interact with a detector on one side and a supercomputer on the other side with a simple webpage called Distiller in the middle,” said Peter Ercius, interim facility director of the National Center for Electron Microscopy (NCEM) at Berkeley Lab’s Molecular Foundry. “We’re moving towards getting huge amounts of data processed in an automated way with minimal human intervention.”
Apr 16, 20253 min read
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